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low tension chemical compound hexamethyldisilazane  (Thermo Fisher)


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    Thermo Fisher low tension chemical compound hexamethyldisilazane
    Low Tension Chemical Compound Hexamethyldisilazane, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/compound+36/Hexamethyldisilazane%2C+Electronic+grade%2C+99%2B%25/10__1016_slash_j__apmt__2026__103136-145-20-28
    Average 94 stars, based on 1 article reviews
    low tension chemical compound hexamethyldisilazane - by Bioz Stars, 2026-09
    94/100 stars

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    Related Articles

    Inhibition:

    Article Title: Discovery and Optimization of Potent, Efficacious and Selective Inhibitors Targeting EGFR Exon20 Insertion Mutations
    Article Snippet: Compounds were screened for known PAINS substructures, using SMARTS definitions curated by OpenEye Scientific and adapted from the SLN patterns from Baell and Holloway.1 All compounds were found to be clean against all filters. .. %inhibition data for compound 36 tested at 0.1 μM concentration at ThermoFisher .. Inhibition (%) Kinase Name Mean Inhibition (%) AAK1 -0.044 LYN A 18 ABL1 3.4 MAP2K1 (MEK1) 12 ABL2 (Arg) 11 MAP3K7/MAP3K7IP1 (TAK1-TAB1) 5.6 ACVR1B (ALK4) 5.9 MAP3K9 (MLK1) -6.7 AKT1 (PKB alpha) 3.4 MAP4K1 (HPK1) 19 AKT2 (PKB beta) 6.9 MAP4K3 (GLK) 38 ALK 4.7 MAPK1 (ERK2) 1.6 AMPK A2/B1/G1 4.4 MAPK14 (p38 alpha) Direct 4.9 AURKB (Aurora B) 5.9 MAPK8 (JNK1) 8.2 AURKC (Aurora C) -12 MAPKAPK2 5.9 AXL 6.4 MAPKAPK5 (PRAK) -1 BLK 51 MARK1 (MARK) 10 BMX 90 MARK2 7.9 BRAF 6.6 MERTK (cMER) 0.56 BTK 99 MET (cMet) 25 CAMK1 (CaMK1) -9.2 MINK1 55 CAMK2B (CaMKII beta) 0.48 MKNK2 (MNK2) 12 CDK1/cyclin B 5.6 MST1R (RON) 15 CDK2/cyclin A 4.9 MYLK (MLCK) 4.9 CDK2/cyclin E1 19 NEK2 18 CDK7/cyclin H/MNAT1 1.3 NTRK1 (TRKA) 32 CDK8/cyclin C 12 NTRK2 (TRKB) -0.90 CDK9/cyclin T1 17 NTRK3 (TRKC) 17 CHEK1 (CHK1) 32 NUAK1 (ARK5) -3.3 CLK1 8.5 PAK1 22 CLK2 3 PAK2 (PAK65) 15 CLK3 -4.3 PAK4 9.9 CLK4 1.7 PAK7 (KIAA1264) 15 CSF1R (FMS) 8.7 PDGFRB (PDGFR beta) 3.4 CSNK1G1 (CK1 gamma 1) 2.3 PDK1 6.6 CSNK2A2 (CK2 alpha 2) 9.9 PEAK1 4.3 DDR2 0.60 PI4KB (PI4K beta) 22 DMPK 1.9 PIK3C2A (PI3K-C2 alpha) 4.7 DNA-PK 18 PIK3C3 (hVPS34) 4.3 DYRK2 6.9 PIK3CA/PIK3R1 (p110 alpha/p85 alpha) 16 S16 EEF2K 8.2 PIK3CB/PIK3R1 (p110 beta/p85 alpha) -11 EGFR (ErbB1) 38 PIK3CD/PIK3R1 (p110 delta/p85 alpha) 8.5 EGFR (ErbB1) T790M L858R 18 PIK3CG (p110 gamma) 7.3 EPHA5 4.1 PIM2 6.8 EPHB1 3 PLK1 11 EPHB4 8.3 PRKACA (PKA) -0.82 ERBB2 (HER2) 77 PRKCA (PKC alpha) 12 ERBB4 (HER4) 99 PRKCE (PKC epsilon) 4.5 FER 9.4 PRKCQ (PKC theta) -5.6 FES (FPS) 4 PRKG1 3.1 FGFR1 6.7 PTK2 (FAK) 10 FGFR1 V561M 4 PTK6 (Brk) 3.4 FGFR2 5.1 RAF1 (cRAF) Y340D Y341D 0.31 FGFR3 -0.24 RET 6 FGFR4 -3.7 RET V804L 7.3 FLT1 (VEGFR1) 6.5 RET V804M 3.8 FLT3 13 ROCK1 6.2 FRAP1 (mTOR) -3 ROCK2 14 FYN 4.1 ROS1 10 GSG2 (Haspin) -13 RPS6KA1 (RSK1) -1.6 GSK3A (GSK3 alpha) 1.5 RPS6KA5 (MSK1) -1.2 GSK3B (GSK3 beta) -1.3 RPS6KB1 (p70S6K) -1.7 IGF1R 3.9 SGK (SGK1) 7.5 IKBKB (IKK beta) 4.3 SRC 11 INSR 5.9 SRPK1 5.1 INSRR (IRR) 16 STK17A (DRAK1) 12 IRAK1 -15 STK4 (MST1) 6.7 IRAK4 -3.2 SYK 3.7 JAK1 1.3 TBK1 9.8 JAK2 11 TGFBR1 (ALK5) 3.6 JAK3 3.3 TNIK 57 KDR (VEGFR2) 1.5 TYRO3 (RSE) -27 KIT 19 ULK2 -1.8 LCK 21 YES1 12 LRRK2 -16 ZAP70 14

    Article Title: Optimization of an Imidazo[1,2- a ]pyridine Series to Afford Highly Selective Type I1/2 Dual Mer/Axl Kinase Inhibitors with In Vivo Efficacy.
    Article Snippet: .. %inhibition data for compound 36 tested at 1 μM concentration at ThermoFisher ..

    Concentration Assay:

    Article Title: Discovery and Optimization of Potent, Efficacious and Selective Inhibitors Targeting EGFR Exon20 Insertion Mutations
    Article Snippet: Compounds were screened for known PAINS substructures, using SMARTS definitions curated by OpenEye Scientific and adapted from the SLN patterns from Baell and Holloway.1 All compounds were found to be clean against all filters. .. %inhibition data for compound 36 tested at 0.1 μM concentration at ThermoFisher .. Inhibition (%) Kinase Name Mean Inhibition (%) AAK1 -0.044 LYN A 18 ABL1 3.4 MAP2K1 (MEK1) 12 ABL2 (Arg) 11 MAP3K7/MAP3K7IP1 (TAK1-TAB1) 5.6 ACVR1B (ALK4) 5.9 MAP3K9 (MLK1) -6.7 AKT1 (PKB alpha) 3.4 MAP4K1 (HPK1) 19 AKT2 (PKB beta) 6.9 MAP4K3 (GLK) 38 ALK 4.7 MAPK1 (ERK2) 1.6 AMPK A2/B1/G1 4.4 MAPK14 (p38 alpha) Direct 4.9 AURKB (Aurora B) 5.9 MAPK8 (JNK1) 8.2 AURKC (Aurora C) -12 MAPKAPK2 5.9 AXL 6.4 MAPKAPK5 (PRAK) -1 BLK 51 MARK1 (MARK) 10 BMX 90 MARK2 7.9 BRAF 6.6 MERTK (cMER) 0.56 BTK 99 MET (cMet) 25 CAMK1 (CaMK1) -9.2 MINK1 55 CAMK2B (CaMKII beta) 0.48 MKNK2 (MNK2) 12 CDK1/cyclin B 5.6 MST1R (RON) 15 CDK2/cyclin A 4.9 MYLK (MLCK) 4.9 CDK2/cyclin E1 19 NEK2 18 CDK7/cyclin H/MNAT1 1.3 NTRK1 (TRKA) 32 CDK8/cyclin C 12 NTRK2 (TRKB) -0.90 CDK9/cyclin T1 17 NTRK3 (TRKC) 17 CHEK1 (CHK1) 32 NUAK1 (ARK5) -3.3 CLK1 8.5 PAK1 22 CLK2 3 PAK2 (PAK65) 15 CLK3 -4.3 PAK4 9.9 CLK4 1.7 PAK7 (KIAA1264) 15 CSF1R (FMS) 8.7 PDGFRB (PDGFR beta) 3.4 CSNK1G1 (CK1 gamma 1) 2.3 PDK1 6.6 CSNK2A2 (CK2 alpha 2) 9.9 PEAK1 4.3 DDR2 0.60 PI4KB (PI4K beta) 22 DMPK 1.9 PIK3C2A (PI3K-C2 alpha) 4.7 DNA-PK 18 PIK3C3 (hVPS34) 4.3 DYRK2 6.9 PIK3CA/PIK3R1 (p110 alpha/p85 alpha) 16 S16 EEF2K 8.2 PIK3CB/PIK3R1 (p110 beta/p85 alpha) -11 EGFR (ErbB1) 38 PIK3CD/PIK3R1 (p110 delta/p85 alpha) 8.5 EGFR (ErbB1) T790M L858R 18 PIK3CG (p110 gamma) 7.3 EPHA5 4.1 PIM2 6.8 EPHB1 3 PLK1 11 EPHB4 8.3 PRKACA (PKA) -0.82 ERBB2 (HER2) 77 PRKCA (PKC alpha) 12 ERBB4 (HER4) 99 PRKCE (PKC epsilon) 4.5 FER 9.4 PRKCQ (PKC theta) -5.6 FES (FPS) 4 PRKG1 3.1 FGFR1 6.7 PTK2 (FAK) 10 FGFR1 V561M 4 PTK6 (Brk) 3.4 FGFR2 5.1 RAF1 (cRAF) Y340D Y341D 0.31 FGFR3 -0.24 RET 6 FGFR4 -3.7 RET V804L 7.3 FLT1 (VEGFR1) 6.5 RET V804M 3.8 FLT3 13 ROCK1 6.2 FRAP1 (mTOR) -3 ROCK2 14 FYN 4.1 ROS1 10 GSG2 (Haspin) -13 RPS6KA1 (RSK1) -1.6 GSK3A (GSK3 alpha) 1.5 RPS6KA5 (MSK1) -1.2 GSK3B (GSK3 beta) -1.3 RPS6KB1 (p70S6K) -1.7 IGF1R 3.9 SGK (SGK1) 7.5 IKBKB (IKK beta) 4.3 SRC 11 INSR 5.9 SRPK1 5.1 INSRR (IRR) 16 STK17A (DRAK1) 12 IRAK1 -15 STK4 (MST1) 6.7 IRAK4 -3.2 SYK 3.7 JAK1 1.3 TBK1 9.8 JAK2 11 TGFBR1 (ALK5) 3.6 JAK3 3.3 TNIK 57 KDR (VEGFR2) 1.5 TYRO3 (RSE) -27 KIT 19 ULK2 -1.8 LCK 21 YES1 12 LRRK2 -16 ZAP70 14

    Article Title: Optimization of an Imidazo[1,2- a ]pyridine Series to Afford Highly Selective Type I1/2 Dual Mer/Axl Kinase Inhibitors with In Vivo Efficacy.
    Article Snippet: .. %inhibition data for compound 36 tested at 1 μM concentration at ThermoFisher ..



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